Title Methods for preparation of apremilast
Year 2021
Country TW、US
Inventor WU, HSYUEH LIANG
Co-inventor WU, PING YU; SYU, JIN-FONG; JULIAN P., HENSCHKE
Cert. No. I733294、US11,008,288B1
Introduction The present invention discloses a method for preparation of Apremilast. β-phthalimino vinylsulfones are reacted through the asymmetric addition reaction to form an addition product, and the drug of Apremilast can be obtained from the addition product through simple reactions. The method is a process for synthesizing Apremilast in a more efficient way.
Validity 2040/02/26
Domain Medicine_and_Health
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