Title | Methods for preparation of apremilast |
Year | 2021 |
Country | TW、US |
Inventor | WU, HSYUEH LIANG |
Co-inventor | WU, PING YU; SYU, JIN-FONG; JULIAN P., HENSCHKE |
Cert. No. | I733294、US11,008,288B1 |
Introduction | The present invention discloses a method for preparation of Apremilast. β-phthalimino vinylsulfones are reacted through the asymmetric addition reaction to form an addition product, and the drug of Apremilast can be obtained from the addition product through simple reactions. The method is a process for synthesizing Apremilast in a more efficient way. |
Validity | 2040/02/26 |
Domain | Medicine_and_Health |
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