| Title | Method for treating abnormal polyglutamine-mediated disease |
| Year | 2015 |
| Country | TW、US |
| Inventor | LEE-CHEN, GUEY-JEN |
| Co-inventor | HSIEH, HSIU MEI; YAO, CHING FA |
| Cert. No. | I484956、US9,393,229B2 |
| Introduction | A method for treating an abnormal polyglutamine-mediated disease is disclosed, wherein indole and an indole-based compound contained in a pharmaceutical composition used in the method of the present invention can reduce the polyglutamine aggregation through decreasing reactive oxygen species production and increasing the activity of chaperone and autophagy. |
| Validity | 2034/12/18 |
| Domain | Medicine_and_Health |
View count:
186