Title Method for treating tau-associated diseases
Year 2017
Country TW、US
Inventor LEE-CHEN, GUEY-JEN
Co-inventor HSIEH, HSIU MEI; LEE, GUAN CHIUN; SUN, YING CHIEH
Cert. No. I587860、US9,629,835B1
Introduction A method for treating tau-associated disease by administering a pharmaceutical composition comprising a quinoline derivative to a subject in need is disclosed. Particularly, a method for treating Alzheimer's disease by administering a pharmaceutical composition comprising a quinoline derivative to a subject in need is disclosed. The two disclosed quinoline derivatives have the inhibition effect for GSK-3β kinase activity, so as the two disclosed quinoline derivatives have the ability for inhibiting tau hyperphosphorylation or reducing tau aggregation.
Validity 2036/08/15
Domain Medicine_and_Health
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