| Title | Pharmaceutical composition and methods for using the same |
| Year | 2019 |
| Country | TW、US、JP、CH、IT、ES、FR、GB、SE、DE |
| Inventor | CHEN, CHIA-CHUN |
| Co-inventor | SU, WU-CHOU; CHEN, HAI-WEN; TSAI, TSUNG-LIN; SHIEH, DAR-BIN |
| Cert. No. | I 674114、US 10,806,801 B2、特許第6921312號、3412281、3412281、3412281、3412281、3412281、3412281、3412281、3412281 |
| Introduction | A pharmaceutical composition includes a plurality of metal nanoparticles and at least one therapeutic agent. Each of the metal nanoparticles includes a core and a stabilizing agent coated on a surface of the core. The at least one therapeutic agent is attached to the stabilizing agent of the metal nanoparticles. Each of the therapeutic agent is an amphiphilic compound and has at least one hydrophobic chain interacting with the stabilizing agent. The pharmaceutical composition may further include a polymer shell encapsulating the metal nanoparticles and the therapeutic agent for enabling controlled release of the therapeutic agent. The pharmaceutical compositions are bifunctional and may be used for diagnosing and treating cancer. Methods for using the pharmaceutical compositions in conjunction with radiation therapy to diagnose and treat cancer are also provided. |
| Validity | 2038/06/06 |
| Domain | Medicine_and_Health |
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